Their management is complex owing to their clinical variation. Moreover, they spread to the non-motor regions and manifest as a multisystem disorder leading to sensory and cognitive impairment. The low survival period has urged the development of an effective treatment modality. Stem cells hold the key to regeneration, rendering them as suitable therapeutic candidates.
Understanding the Disease
Motor neurons govern the movement of muscles, thus controlling activities like walking, breathing, swallowing, etc. These neurons, or nerve cells relay signals between the brain, spinal cord, and muscles. The brain conveys signals to the spinal cord via upper motor neurons, and spinal cord transmits them to the muscles via lower motor neurons. The clinical heterogeneity has divided these diseases into diverse categories. One category is based on the involvement of upper or lower motor neurons, dividing Motor Neuron Diseases into the following four types.
Amyotrophic Lateral Sclerosis: It affects both upper and lower motor neurons.
Read More: https://advancells.blogspot.com/2025/10/motor-neuron-diseases-promise-of.html
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